Search results for " Spatial heterogeneity"
showing 3 items of 3 documents
Santa Rosalia, the icon of biodiversity
2010
This article summarizes the results presented in a series of invited contributions which were submitted to celebrate the fiftieth anniversary of publication of the seminal article ‘‘Homage to Santa Rosalia or why are there so many kinds of animals’’ by G.E. Hutchinson. The authors were asked to explore old and new paradigms of biodiversity in aquatic ecosystems. The contributions by Hutchinson in this field are truly landmarks in the history of modern ecological sciences. The authors of the contributed articles, stimulated by one of the most fruitful concept articles in ecology that has appeared over the last half century, have shown that scientific investigation, although still seeking the…
Self-Organization Pathways and Spatial Heterogeneity in Insulin Amyloid Fibril Formation
2009
At high temperature and low pH, the protein hormone insulin is highly prone to form amyloid fibrils, and for this reason it is widely used as a model system to study fibril formation mechanisms. In this work, we focused on insulin aggregation mechanisms occurring in HCl solutions (pH 1.6) at 60 degrees C. By means of in situ Thioflavin T (ThT) staining, the kinetics profiles were characterized as a function of the protein concentration, and two concurrent aggregation pathways were pointed out, being concentration dependent. In correspondence to these pathways, different morphologies of self-assembled protein molecules were detected by atomic force microscopy images also evidencing the prese…
Hétérogénéité spatiale : principes et méthodes
2004
Spatial Heterogeneity : Principles and Methods This article has a dual purpose . First , it describes the main econometric specifications which can be used to represent spatial heterogeneity , reflected in an instability of parameters in space and / or a heteroscedasticity of error terms . Only the specifications valid in cross-section are examined . Second , it explains the links between spatial heterogeneity and autocorrelation , the other major feature of localised data , defined by the absence of independence between geographical observations . In particular , we look at the extent to which traditional tests of heteroscedasticity or instability need to be amended to take account of spat…